Endocrinology Department

The Endocrinology Department of Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University was established in 1999 and officially established in 2002. It is the first gynecological endocrinology department in China. The chief expert, founding director and subject leader is Professor Ruan Xiangyan, MD (postdoctoral), a visiting scholar at the University of Tübingen in Germany. Chair Professor, Representative to the 14th National People’s Congress, 4th Executive Deputy Director of the Department of Obstetrics and Gynecology, Capital Medical University, Head of the Beijing Strategic Science and Technology Team, Expert with Special Government Allowances from the State Council, China’s Good Doctor, Top Ten Health Guardians in the Capital, Beijing’s Good Doctor, National Science Popularization Expert, Beijing Health science expert, he serves as vice president of the Beijing Society of Obstetrics and Gynecology, chairman of the Endocrinology Branch, chairman of the Fertility Protection and Preservation Professional Committee of the China Association for the Promotion of Human Health Science and Technology, vice chairman of the Osteoporosis and Bone Mineral Salts Branch of the Beijing Medical Association, member of the Executive Committee of the International Society of Gynecological Endocrinology, and National Member of the Executive Committee of the International Society of Menopause, Advisory Member of the Executive Committee of the European Society of Menopause and Menopause, Member of the International Society of Human Reproduction, Chairman of the China Gynecological Endocrinology Branch of the International Society of Gynecological Endocrinology, and "Gynecological," the official journal of the International Society of Gynecological Endocrinology. Endocrinology" associate editor and its Chinese version chief editor, etc.

He has published more than 500 papers and more than 150 SCI papers. He has been successfully selected into the top 2% of the world's top scientists in the field of obstetrics, gynecology and reproductive medicine for three consecutive years from 2022 to 2024.

It is an international leader in the fields of menopause, gynecological endocrinology and fertility protection. It has taken the lead in formulating 13 standards, guidelines and consensuses and edited 9 books.

Academic achievements

1. Create China's first ovarian tissue cryopreservation bank, and be the first, only and internationally leading company in the field of fertility protection for ovarian tissue cryopreservation and transplantation.

In 2012, Director Ruan Xiangyan, as the founder and person in charge, led the team to create China's first ovarian tissue cryopreservation bank. She led the team to successfully complete China's first cryopreserved ovarian tissue transplantation, and achieved China's first natural pregnancy after cryopreserved ovarian tissue transplantation and the birth of the first healthy cryopreserved baby. These three important breakthroughs filled a gap in the history of fertility protection in China and promoted the major scientific and technological transformation of ovarian tissue cryopreservation and transplantation technology in China.

The ovarian tissue cryopreservation team led by Professor Ruan Xiangyan from Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University has so far cryopreserved ovarian tissue from 800 children and young patients, covering nearly 80 kinds of diseases. The youngest patient is only 6 months old.

41 cases of transplantation have been successfully completed, and there has been no recurrence of the primary disease related to transplantation. The transplantation success rate has reached 100%, which is at an internationally leading level.

The standard for internationally mature ovarian tissue cryopreservation centers is to perform 10 or more cases of cryopreserved ovarian tissue transplantation. The success rate of one transplantation exceeds 70% and a healthy child is born.

There are only more than 20 mature centers in the world, and the ovarian tissue cryopreservation bank of Professor Ruan Xiangyan’s team at Beijing Obstetrics and Gynecology Hospital is the only mature center in China among them.

Technologies related to ovarian tissue cryopreservation and transplantation have obtained 4 national invention patents.

Ruan Xiangyan’s team has won the second prize of the Beijing Science and Technology Progress Award, the first prize of the National Maternal and Child Health Science and Technology Award, and the first prize of the China Invention Association’s Invention and Entrepreneurship Achievement Award.

2. Establish China's first gynecological endocrinology specialty - known as the world's largest gynecological endocrinology specialty due to its academic achievements

In 2002, Professor Ruan Xiangyan, as the director of the Innovation Department, took the lead in establishing the Department of Gynecological Endocrinology in China.

The department currently has 17 on-the-job medical staff and researchers, 15 doctoral and master's degree candidates, and 11 foreign high-end talent (category A) experts.

Among them, Professor Mu Ke and Professor Rabe won the Chinese Government Friendship Award, the highest award for foreign friends in China, and Professor Matthew Corey won the Beijing Great Wall Friendship Award. In 2018, the gynecological endocrinology application of Beijing Obstetrics and Gynecology Hospital was approved as one of the first batch of talent introduction demonstration bases of the Ministry of Science and Technology.

From 2020 to 2024, visiting professor Miu Ke has been selected into the top 2% of the world's top scientists many times.

The department has trained nearly 80 postdoctoral, doctoral, and master's students.

In 2020, Professor Ruan Xiangyan led 102 medical institutions across the country to carry out the "National Multi-center Clinical Study on Premature Ovarian Insufficiency (POI)", established the largest POI database in the world, conducted in-depth research on the prevention and treatment of different causes of POI, and formulated 3 relevant guidelines and group standards, providing Chinese solutions for the international community.

The Endocrinology Department of Beijing Obstetrics and Gynecology Hospital is hailed as the largest gynecological endocrinology specialty in the world by the International Society of Gynecological Endocrinology. The subject leader Ruan Xiangyan was invited to participate in the revision of the international POI guidelines. The updated version of the 2024 international PO1 guidelines was published in three top journals in the field. Ruan Xiangyan is the only guideline expert in China.

Ruan Xiangyan is also the first and only expert in China elected to be an executive member of the International Society of Gynecological Endocrinology and a committee member of the International Society of Human Reproduction.

At the World Congress on Human Reproduction in September 2025, Ruan Xiangyan was invited to give conference reports on "Managing the world's largest gynecological endocrinology patient with polycystic ovary syndrome" and "New technologies and clinical experience in ovarian tissue cryopreservation and transplantation from China's first ovarian tissue cryopreservation bank."

3. Establish China's first comprehensive menopause management center, which is recognized by the International Menopause Society as the world's largest menopause clinic. Its standard menopause management level is in a leading position domestically and internationally.

In 1999, Professor Ruan Xiangyan took the lead in establishing the first comprehensive menopause guidance center in China, established a quality assurance system for menopausal health care treatment, and took the lead in carrying out comprehensive, multi-level and individualized health care treatment for menopausal women, becoming a national model.

In 2011, the Chinese Hospital Association and the Chinese Medical Association jointly awarded China's first "Menopause Clinic Project Center". In 2017, it was rated as "the first batch of Beijing Menopause Health Care Specialty Demonstration Units". In 2020, it was rated as a "National Menopause Health Care Specialty Construction Unit". Director Ruan Xiangyan led the team to become A model of standardized health care treatment for menopausal-related issues across the country, the Scientific Committee of the International Menopause Society recognized the Menopause Clinic of Beijing Obstetrics and Gynecology Hospital as the largest menopause clinic in the world. In October 2024, Ruan Xiangyan was invited to give a conference report on "Managing the World's Largest Menopause Clinic" at the 18th World Menopause Congress.

Ruan Xiangyan is the first and only Chinese expert to be elected as a member of the Executive Committee of the International Menopause Society.