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Chen Zan
Chief Physician Professor Doctoral Supervisor

Xuanwu Hospital, Capital Medical University · Neurology Department · Beijing

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4. (PFDF),,,,. 3D,. ACAF.: 1992-9 1999-9 2000-9 2003-9 2003-9 2005-9 2008: 、.1), PFDF; 、,,.2), TGF-β; VEGFR TGF-β, CAR-T,; B7-H3 IL-7, B7-H3/IL-7 CAR-T,. 、 、 “ ” 、. 《 》;《 》、《 》,《 》. 2. SCI 、;.:: 1. Duan W, Zhang B, Li X, et al. Single-cell transcriptome profiling reveals intra-tumoral heterogeneity in human chordomas[J]. Cancer Immunology, Immunotherapy, 2022, 71(9): 2185-2195. 2. Wu H, Li X, Zhang B, et al. Single-cell sequencing reveals VEGFR as a potential target for CAR-T cell therapy in chordoma[J]. British Journal of Cancer, 2024, 130(10): 1609-1620. 3. Wu H, Xu Z, Qi M, et al. Interleukin-7 expression by CAR-T cells improves CAR-T cell survival and efficacy in chordoma[J]. Cancer Immunology, Immunotherapy, 2024, 73(10): 188. 4. Duan W, Chou D, Jiang B, et al. Posterior revision surgery using an intraarticular distraction technique with cage grafting to treat atlantoaxial dislocation associated with basilar invagination[J]. Journal of Neurosurgery: Spine, 2019, 31(4): 525-533. 5. Guan J, Jian F, Yao Q, et al. Quantitative reduction of basilar invagination with atlantoaxial dislocation by a posterior approach[J]. Neurospine, 2020, 17(3): 574. 6.,,,. [J]., 2019, 57(10):6.

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