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Li Xiao Xin
Professor · Chief Physician

Peking University People's Hospital · Ophthalmology Department · Beijing

1987,, 、 、. “ ”、 “973”、“863”、 “985”、“211” WHO, (973 ) 、“985”. 245, SCI 67,, FASEB J、 Ophthalmology、Plos One、IOVS, 140. 5. 20,,.,,. 、 、 、 16.2007 “ ”,2008,2009,2011,. 1995/07 –1995/10,, 1991/01 –1991/10 Tuebingen,, 1982/09 –1986/07 Essen,, 1971/01 –1976/07,, 2009/05 –2015, 2009/05 –2015,, 1993/12 –2015,, 1992/12 –2015,, 1991/12 –2015,, 1988/12 –1993/12,, 1986/12 –1991/12,, / 1976/12 –1981/12,,: 、 、 、 、 、 、 、.:: 1. Cheng Y, Huang L, Li X*, Zhou P, Zeng W, Zhang C. Genetic and Functional Dissection of ARMS2 in Age-Related Macular Degeneration and PolypoidalChoroidalVasculopathy. PLoS One. 2013;8(1):e53665. 2. Jiang JJ, Wu X, Zhou P, Yu WZ, Huang LZ, Li XX*. Meta-analysis of the relationship between the LOC387715/ARMS2 polymorphism and polypoidalchoroidalvasculopathy. Genet Mol Res. 2012;11(4):4256-67. 3. Miao H, Wu BD, Tao Y, Li XX*. Diffusion of macromolecules through sclera. ActaOphthalmol. 2013;91(1):e1-6. 4. Chen WC, Wang Y, Li XX*. Morphologic and functional evaluation before and after successful macular hole surgery using spectral-domain optical coherence tomography combined with microperimetry. Retina. 2012;32(9):1733-42. 5. Sun C, Zhao M, Li X*. CFB/C2 gene polymorphisms and risk of age-related macular degeneration: a systematic review and meta-analysis. Curr Eye Res. 2012;37(4):259-71. 6. Li XX*, Tao Y. Small laser spot versus standard laser spot photodynamic therapy for idiopathic choroidal neovascularization: a randomized controlled study. Chin Med J (Engl). 2012;125(24):4424-8. 7. Jun Tian, Xueying Qin, Wenzhen Yu, Jing Hou, Juan Li, Kai Fang,Dafang Chen, Yonghua Hu, Xiaoxin Li*. Association of Genetic Polymorphisms and Age-related Macular Degeneration in Chinese population. IOVS,2012; 53:4262-426. 8. Xiaoxin Li*, Yonghua Hu, Xiaodong Sun, Junjun Zhang, Maonian Zhang.Bevacizumab for Neovascular Age-related Macular Degeneration in China. Ophthalmology 2012; 119:2087-2093 9. Jun Tian, Xueying Qin, Kai Fang, Qing Chen, Jing Hou, Juan Li, Wenzhen Yu, Dafang Chen, Yonghua Hu,Xiaoxin Li*. Association of genetic polymorphisms with response to bevacizumab for neovascular age-related macular degeneration in the Chinese population. Pharmacogenomics. 2012;13(7):779-787. 10. Yaoyao Sun, Wenzhen Yu, Lvzhen Huang, Jing Hou, Peihua Gong, Yi Zheng, Mingwei Zhao, Peng Zhou, Xiaoxin Li*. Is Asthma Related to Choroidal Neovascularization? PLoS One. 2012; 7(5): e35415. 11. Bai YJ, Huang LZ, Xu XL, Du W, Zhou AY, Yu WZ, Li XX*. Polyethylene Glycol-Modified Pigment Epithelial-Derived Factor: New Prospects for Treatment of Retinal Neovascularization. Journal of Pharmacology and Experimental Therapeutics, 2012, 342(1):131-139. 12. Heng Miao, Yong Tao, Xiao-xin Li*. Inflammatory cytokines in aqueous humor of patients with choroidal neovascularization.Mol Vis. 2012; 18: 574-580. 13. Jingfeng Qu, Xiaoxin Li*.Vitrectomy Outcomes in Eyes with High Myopic Macular Hole without Retinal Detachment. Retina. 2012, 32(2):275-280. 14. Sun Chuan, Min Zhao, Xiaoxin Li*.CFB/C2 gene polymorphisms and risk of age-related macular degeneration: a systematic review and meta-analysis. CURR EYE RES. 2012. 37(4):259-271 15. Wei Du, Wenzhen Yu, Xiaoxin Li*. Ephrin-A4 is involved in retinal neovascularization by regulating the VEGF signaling pathway. IOVS, 2012:53(4):1990-1998 16. Wang K, Li XQ, Li XX*, Pei WH, Chen HD, Dong JQ. Efficacy and reliability of long-term implantation of multi-channel microelectrode arrays in the optical nerve sheath of rabbit eyes. Vision Res. 2011;51(17):1897-906. 17. Zhou WY, Yu WZ, Xie WK, Huang LZ, Xu YS, Li XX*. The role of SLIT-ROBO signaling in proliferative diabetic retinopathy and retinal pigment epithelial cells. Mol Vis. 2011;17:1526-36. 18. Hou J, Tao Y, Li XX*, Zhao MW.Clinical characteristics of polypoidalchoroidalvasculopathy in Chinese patients. Graefes Arch ClinExpOphthalmol. 2011;249(7):975-9. 19. Zhao M, Shi X, Liang JH, Miao Y, Xie WK, Zhang Y, Li XX*. Expression of pro- and anti-angiogenic isoforms of VEGF in the mouse model of oxygen-induced retinopathy. Exp Eye Res. 2011;93(6):921-6. 20. Zhao M, Li XX*. Macular retinoschisis associated with normal tension glaucoma.Graefes Arch ClinExpOphthalmol. 2011;249(8):1255-8. 21. Xie WK, Yu WZ, Zhao M, Zhou WY, Chen H, Du W, Huang LZ, Xu YS, Li XX*. Protective effect of paeoniflorin against oxidative stress in human retinal pigment epithelium in vitro. Mol Vis. 2011;17:3512-3522. 22. Zhou P, Fan L, Yu KD, Zhao MW, Li XX*. Toll-like receptor 3 C1234T may protect against geographic atrophy through decreased dsRNA binding capacity. FASEB J. 2011;25(10):3489-95. 23. Qu JF, Zhao MW, Jiang YR, Li XX*.Vitrectomy outcomes in eyes with high myopic macular hole without retinal detachment.Retina. 2012;32(2):275-80. 24. Huang LZ, Xu YS, Yu WZ, Li Y, Chu LQ, Dong JQ, Li XX*. Effect of Robo1 on retinal pigment epithelial cells and experimental proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 2010;51(6):3193-3204. 25. Jia LY, Li XX*, Yu WZ, Zeng WT, Liang C. Novel frizzled-4 gene mutations in chinese patients with familial exudative vitreoretinopathy. Arch Ophthalmol. 2010;128(10):1341-1349. 26. Qi HJ, Li XX*, Tao Y. Outcome of intravitreal bevacizumab for idiopathic choroidal neovascularization in a Chinese population. Can J Ophthalmol. 2010;45(4):381-385. 27. Qu J, Bao Y, Li M, Zhao M, Li X*. Surgical management of late capsular block syndrome. J Cataract Refract Surg. 2010;36(10):1687-1691. 28. Wang Y, Bian ZM, Yu WZ, Yan Z, Chen WC, Li XX*. Induction of interleukin-8 gene expression and protein secretion by C-reactive protein in ARPE-19 cells. Exp Eye Res. 2010;91(2):135-142. 29. Yong Tao, Yan-Rong Jiang, Xiao-Xin Li, Lei Gao, Jost B Jonas*. Long-term results of vitrectomy without endotamponade in proliferative diabetic retinopathy with tractional retinal detachment. Retina. 2010; 30(3):447-51. 30. Chen Y, Li XX*, Yin H, Gilbert C, Liang JH, Jiang YR, Zhao MW, Beijing Rop Survey G. Risk factors for retinopathy of prematurity in six neonatal intensive care units in Beijing, China; British Journal of Ophthalmology, Br J Ophthalmol. 2008,92:326-30. 31. Zhang T, Li X*, Yu W, Yan Z, Zou H, He X. Overexpression of Thymosin Beta-10 Inhibits VEGF mRNA Expression, Autocrine VEGF Protein Production, and Tube Formation in Hypoxia-Induced Monkey Choroid-Retinal Endothelial Cells. Ophthalmic Res. 2008;41(1):36-43. 32. Pei X, Bao Y, Chen Y, Li X*. Correlation of lens density measured using the PentacamScheimpflug system with the Lens Opacities Classification System III grading score and visual acuity in age-related nuclear cataract.Br J Ophthalmol. 2008;92(11):1471-5. 33. Yu WZ, Zou H, Li XX*, Yan Z, Dong JQ. Effects of the phosphatidylinositol 3-kinase inhibitor in a mouse model of retinal neovascularization. Ophthalmic Res. 2008;40(1):19-25 34. Zhou P, Zhao MW, Li XX*, Hu XF, Wu X, Niu LJ, Yu WZ, Xu XL.A new method of extrapolating the sweep pattern visual evoked potential acuity. Doc Ophthalmol. 2008;117(2): 85-91. 35. Ma X, Li X*, Wang L.Novel XLRS1 gene mutations cause X-linked juvenile retinoschisis in Chinese families. Jpn J Ophthalmol. 2008;52(1):48-51 36. Guo LL, Yu WZ, Li XX*, Zhao G, Liang JH, He PY, Wang K, Zhou P, Jiang YR, Zhao MW.Targeting of integrin-linked kinase with a small interfering RNA suppresses progression of experimental proliferative vitreoretinopathy. Exp Eye Res. 2008;87(6):551-60. 37. Zhang TH, Li XX*, Yu WZ, Yan Z, Zou H, He XJ. Overexpression of Thymosin Beta-10 Inhibits VEGF mRNA Expression, Autocrine VEGF Protein Production, and Tube Formation in Hypoxia-Induced Monkey Choroid-Retinal Endothelial Cells. Ophthalmic Res. 2008;41(1):36-43. 38. Li X*, Wang W, Tang S, Zhao J.Gas Injection versus Vitrectomy with Gas for Treating Retinal Detachment Owing to Macular Hole in High Myopes. Ophthalmology. Ophthalmology 2009;116:1182–1187 39. Huang L, Xu Y, Yu W, Li X*, Liqun C, He X, Peiying H:Robo1: a potential role in ocular angiogenesis.Curr Eye Res. 2009;34(12):1019-29 40. Huang L, Yu W, Li X*, Xu Y, Niu L, He X, Dong J, Yan Z:Expression of Robo4 in the fibrovascular membranes from patients with proliferative diabetic retinopathy and its role in RF/6A and RPE cells. Mol Vis. 2009;15:1057-69. 41. Huang L, Yu W, Li X*, Niu L, Li K, Li J.Robo1/robo4: different expression patterns in retinal development. Exp Eye Res. 2009;88(3):583-8. 42. Zhao MW, Peng Zhou, Xiaoxin Li*. Phptodynamictherapyfor acute central serous choriorretinopathy-the safe effective lowest dose of Verteporfin. RETINA. 2009;29(8):1155-1161 43. Zhao MW, Zhou P, Cui X, Wang Y, Li XX*. Manual Small Incision 20-Gauge Pars Plana Vitrectomy. Retina. 2009;29(9):1364-6. 44. Zhang TH, Li XX, Yu WZ, Yan Z, Zou H, He XJ. Overexpression of thymosin beta-10 inhibits VEGF mRNA expression, autocrine VEGF protein production, and tube formation in hypoxia-induced monkey choroid-retinal endothelial cells.Ophthalmic Res. 2009;41(1):36-43.: Earlier Treatment for PCV(,2010) Comprehensive treatment for treating submacular hemorrhages caused by PCV(,2010) Role of Photodynamic therapy and Transpupillary thermal therapy in PCV( WOC,2010) Risk factors of anterior Neovascularization in PDR vitrectomy( WOC,2010) Guideline of PCV treatment(PCV Roundtable,2010) Macular Hole retinal Detachment, Bimanual Techniques (Ophthalmology Schoo,2010) First module 2011 vitreoretinal surgery (Asia-Arvo,2011) Challenges and progress in organizing ophthalmic education in China(, 2011) What do we already know about PCV(,2011): 1. ( 2 )(8 、7 ) 2. 3. ( 7 )(5 ) 4.: 1. 2. 3. “ ” 4. 5. 6.:,,,,,,,,,, | | | |:: 11:100044 ICP: ICP 10005257 -1 COPYRIGHT © 2004-2026:88326666: APP

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