Zhang Bo

1997 8 －: /,. 2004 10 －: /,,; 2008 10 －: /,; 、 、 、 、 、 “ ”. 2, 1.: 1 、:1): TEIF(telomerase transcriptional elements-interacting factor, GenBank: Accession No.AF297709),,. 《Oncogene》、《BBA》, Nature-China;2) NAT10(hALP,human N-acetyltransferase-like protein, GenBank: Accession No.AF496535). NAT10. 《Clin Cancer Res》、《Exp Cell Res》; 2 、: AKT HER2; AKT Girdin 、 、. Bmi1 ER,, p16,, ER; 3 、 －: 1),;.,. 、. 2001 2003;2);3):COUP-TFII、 NAT10 TEIF. - - - 《 》 《 》 《 》、《AIMM》 、 、, 、; 2010:; 2006 ( 6 ); 2003: hTR; 2003 ( 3 ). 2001:; 1996: 、. 1..《 》..1996 3; 2..《 》,.2012 3; (* ): 1. Zhang H, Hou W, Wang H, Liu H, Jia X, Zheng X, Zou Y, Li X, Hou L, McNutt MA and Zhang B*. GSK-3β-regulated N-acetyltransferase 10 is involved in colorectal cancer invasion. Clin Cancer Res. 2014, in press. 2. Zhao J, Zou Y, Liu H, Wang H, Zhang H, Hou W, Li X, Jia X, Zhang J, Hou L, Zhang B*. TEIF associated centrosome activity is regulated by EGF/PI3K/Akt signaling. Biochimica et Biophysica Acta 1843 (2014) 1851–1864. 3. Wang H, Liu H, Li X, Zhao J, Zhang H, Mao J, Zou Y, Zhang H, Zhang S, Hou W, Hou L, McNutt MA and Zhang B*. Estrogen receptor α-coupled Bmi1 regulation pathway in breast cancer and its clinical implications. BMC Cancer 2014, 14:122. 4. Hsu CC, Chen CH, Hsu TI, Hung JJ, Ko JL, Zhang B, Lee YC, Chen HK, Chang WC, and Lin DY. The 58-kDa microspherule protein (MSP58) represses human telomerase reverse transcriptase (hTERT) gene expression and cell proliferation by interacting with telomerase transcriptional element-interacting factor (TEIF). BBA - Mol Cell Res, 2013, 1843(3): 565-579. 5. Jiang P, Cui S, Ren Y, Mao J, Liu H, Tian Y, Liu Y, Du J, Hou L and Zhang B*. Girdin correlated with autophagy in invasive ductal breast carcinomas. Tumori, 2013, 99: 542-546. 6. Wang J, Wang H, Hou W, Liu H, Zou Y, Zhang H, Hou L, McNutt MA and Zhang B*. Subnuclear distribution of SSX regulates its function. Mol Cell Biochem. DOI 10.1007/s11010-013-1684-9. 2013. 7. Chi Y,Zhao J, Cui S, Jiang P, Wang H, Zhang H, Mao J, Liu H, Hou L, Zhang B* The level of phosphorylated Akt predominantly reflects the expressive status of CerbB2 in invasive breast cancer. Histol Histopathol. 2013, 28: 655-661. 8. Mao JZ, Jiang P, Cui SP, Ren YL, Zhao J, Yin XH, Enomoto A, Liu HJ, Hou L, Takahashi M, Zhang B*. Girdin locates in centrosome and midbody and plays an important role in cell division. Cancer Sci.2012, 103: 1780-1787. 9. Ling Y, Jiang P, Cui SP, Ren YL, Zhu SN, Yang JP, Du J, Zhang Y, Liu JY, Zhang B*. Clinical implications for Girdin protein expression in breast cancer. Cancer Investigation, 2011, 29:405–410. 10. Gong Y, Sun Y, Sun Q, Hou L, Liu H, Shen Q, Ling Y, Chi Y and Zhang B*. Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers. Oncogene. 2009, 28: 1549–1560. 11. Sun Y, Sun Q, Gong Y, Wang J, Hou L, Shen Q, Ling Y, Chi Y and Zhang B*. A cluster of polypyrimidine tracts is involved in the transcription regulation of telomerase transcriptional elements-interacting factor. Mol. Cell Biochem. 2009, 327: 65-73. 12. Shen Q, Zheng X, McNutt MA, Guang L, Sun Y, Wang J, Gong Y, Hou L and Zhang B*. NAT10, a nucleolar protein, localizes to midbody and regulates cytokinesis and acetylation of microtubules. Exp. Cell Res. 2009, 315: 1653-1667. 13. Liu H, Ling Y, Gong Y, Sun Y, Hou L and Zhang B*. DNA damage induces N-acetyltransferase NAT10 gene expression through transcriptional activation. Mol Cell Biochem, 2007, 300: 249-258. 14. Ye J, Zhang B, Xu J, Chang Q, McNutt MA, Korteweg C, Gong E, Gu J. Molecular Pathology in the Lungs of Severe Acute Respiratory Syndrome Patients. Am J Pathol. 2007, 170: 538-545 15. Gu J, Xie Z, Gao Z, Liu J, Korteweg C, Ye J, Lau LT, Lu J, Gao Z, Zhang B, McNutt MA, Lu M, Anderson VM, Gong E, Yu AC, Lipkin WI. H5N1 infection of the respiratory tract and beyond: a molecular pathology study. Lancet 2007, 370: 1137-45 16. Li T, Zhang B, Ye Y, Yin H. Immunohistochemical and genetic analysis of Chinese nasal natural killer/T-cell lymphomas. Human Pathol. 2006, 37, 54-60. 17. Ye Y, Li T, Zhang B, Guo Z. Amplification and specific expression of T-bet gene in nasal NK/T-cell lymphoma. Leukemia & Lymphoma. 2007, 48: 168-173. 18. Zhao Y, Zheng J, Ling Y, Hou L, Zhang B*. Transcriptional upregulation of DNA polymerase βby TEIF. Biochem Biophys Res Commun. 2005, 333: 908–916. 19. Tang Z, Zhao Y, Mei F, Yang S, Li X, Lv J, Hou L and Zhang B*. Molecular cloning and characterization of a human gene involved in transcriptional regulation of hTERT. Biochem Biophys Res Commun. 2004, 324: 1324-1333. 20. Wang Q, Bai Z, Li X, Hou L and Zhang B*. The evidences of human Orphan Receptor COUP-TFII inhibiting telomerase activity through decreasing hTERT transcription. Cancer Lett. 2004, 214: 81-90. 21. Huang M, Zhang H, Liu C, Hou L, Zhang B*. Development of single-domain recombinant antibodies to reverse transcriptase domain of human hTERT. Hybridoma and Hybridomics. 2004, 23(4). 255-290. 22. Lv J, Liu H, Wang Q, Tang Z, Hou L and Zhang B*. Molecular cloning of a novel human gene encoding histone acetyltransferase-like protein involved in transcriptional activation of hTERT. Biochem Biophys Res Commun. 2003, 311: 506-513.