Zhao Li Bo

010 ) 82265743: [email protected] ( 2008 ) ( 2003 ) ( 2014, 2024 ) 2021.08-, 、 、, ( TDMCT ), 2015.11-2021.07, 、 、 、 、 、, GCP, 2008.08-2015.10, 、 、 1.: FXR BA-MCY:, 2026.1-2029.12, 48,; 2.: - - ALL TGNs, 2022 -2025, 55,; 3.:, 2018-2021, 2600,; 4.: P-gp HIV-, 2012 ～ 2014, 22,; 5.:, 2017-2020, 80,; 6. -: pH-, 2021-2023, 28,; 7.: Lacticaseibacillus casei Zhang, 2025-2027, 30,; 8.:, 2018-2020, 40,; 9., 2022 -2025, 100,; 10. ——: BGus HSCT, 2026.1-2027.12, 15,; 11. ——: - -PPAR, 2023.1-2024.12, 15,; 12. 1, 1000. I 10,., TDM,,;,,;;,;;; TDM;; NMPA,;; 10 SCI /. 2017, 2021, 1. Jingjing Zhang, Yanni Zhang, Xiao Lu, Jiaqi Han, Luquan Wang, Yubin He, Siyao Jin, Yana Li, Xiangyu Ma, Hao Bing, Dong Mei1*, Libo Zhao*. Colon-targeted microbiota-modulating nanoparticles amplify azathioprine efficacy via gu t microbiota axis remodeling in inflammatory bowel disease. Journal of Nanobiotechnology. 2026 Feb 15. doi: 10.1186/s12951-026-04136-4. (IF 12.6) 2. Jingyang Chen, Yanan Wang, Lei Xu, Xiaona Li*, Libo Zhao*. Exploring the Gut Microbiome and Metabolomic Interactions of Antimetabolite Drugs to Optimize Therapy. Gut Microbes. 2026 Dec 31;18(1): 2638009.doi: 10.1080/19490976.2026.2638009. Epub 2026 Feb 27. ( IF 11.0) 3. Xiangyu Ma, Jiamin Xu, Yanan Wang, Joshua S Fleishman, Hao Bing, Boran Yu, Yanming Li, Letao Bo, Shaolong Zhang, Zhe-Sheng Chen#, Libo Zhao#. Research progress on gene mutations and drug resistance in leukemia. Drug resistance updates. 2025 Mar; 79:101195. doi: 10.1016/j.drup.2024.101195. (IF 21.7) 4. Shaolong Zhang, Boran Yu, Jiamin Xu, Siyao Jin, Yanming Li, Hao Bing, Jueyu Li, Xiangyu Ma, Xianhua Zhang, Libo Zhao#. Quantitative Comparison of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Adults: A Systematic Review and Model-Based Meta-Analysis. Diabetes technology & therapeutics 2025 Feb 06; doi:10.1089/dia.2024.0533. (IF 6.3) 5. Jiamin Xu, Jiaqi Han, Siyao Jin, Boran Yu, Xiaona Li, Xiangyu Ma, Liang Sun, Changkun Li, Libo Zhao#, Xin Ni#. Modulation of mercaptopurine intestinal toxicity and pharmacokinetics by gut microbiota. Biomedicine & Pharmacotherapy 177(2024)116975. (IF 7.5) 6. Xiaona Li, Zhini Liu, Zhuo Li, Xin Xiong, Xianhua Zhang, Changqing Yang#, Libo Zhao#, Rongsheng Zhao#. A simple, rapid and sensitive HILIC LC-MS/MS method for simultaneous determination of 16 purine metabolites in plasma and urine. Talanta 267 (2024)125171. (IF 6.1) 7. Yaru Zou, Wei Gao, Huizhen Jin, Chenmei Mao, Yi Zhang, Xiaoling Wang, Dong Mei#, Libo Zhao#. Cellular uptake and transport mechanism of 6-mercaptopurine nanomedicines for enhanced oral bioavailability. International journal of nanomedicine. 2023; 18:79-94. (IF 6.5) 8. Yaru Zou, Dong Mei, Jinjie Yuan, Jiaqi Han, Jiamin Xu, Ning Sun, Huan He, Changqing Yang, Libo Zhao#. Preparation, Characterization, Pharmacokinetic, and Therapeutic Potential of Novel 6-Mercaptopurine-Loaded Oral Nanomedicines for Acute Lymphoblastic Leukemia. International journal of nanomedicine. 2021, 16:1127-1141. (IF 6.5) 9. Dong Mei, Lidong Gong, Yaru Zou, Dan Yang, Haibin Liu, Yuguang Liang, Ning Sun, Libo Zhao#, Qiang Zhang#, Zhiqiang Lin#. Platelet membrane-cloaked paclitaxel-nanocrystals augment postoperative chemotherapeutical efficacy. Journal of controlled release. 2020,08 10;324:341-353. (IF 11.5) 10.Yunjiao Wu, Xinying Feng, Jiapeng Li, Xiaoling Wang, Changqing Yang#, Libo Zhao#. Model-Based Meta-Analysis in Ankylosing Spondylitis: A Q u antitative Comparison of Biologics and Small Targeted molecules. Clinical pharmacology & therapeutics. 2019, 105(5):1244-1255. (IF 5.5)