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Li Zheng Qian
Associate Chief Physician · Doctoral Supervisor

Peking University Third Hospital · Anesthesia Department · Beijing

PI, 、 、 、 、 、 、; Anesthesiology and Perioperative Science 、 Medical Gas Research 、 BMC Anesthesiology; 《 》、《 》;《 》、《 》、《 》.:: 、 、. 4 、 1 、 / 9; 1,. / SCI 42, H 26; 24, 2; / 12 、 2 、 2 、 1; 、 、 、 4; 、 、. 5: (1) Liu K*, Hong J*, Li Y, Wang Q, Dong R, Liu T, Guo X, Chen L #, Li Z #. A novel postoperative delayed neurocognitive recovery model established based on preoperative rapid eye movement sleep deprivation in adult mice. Int Immunopharmacol. 2025 Mar 26;153:114508. ( Q1, IF=5.6 ) (2) Liu K, Chen L, Mi X, Wang Q, Li Y, Hong J, Wang X, Li Y, Song Y, Yuan Y, Wang J, Han D, Liu T, Yang N, Guo X #, Li Z #. Swimming Exercise Pretreatment Attenuates Postoperative Delirium-Like Behavior in Type 2 Diabetic Rats by Enhancing Mitochondrial Biogenesis Through Activation of SIRT2 Deacetylation. MedComm. 2025;18;6(4):e70142. ( Q1, IF=10.7 ) (3) Hong Jingshu, Li Yue, Chen Lei, Han Dengyang, Li Yitong, Mi Xinning, Liu Kaixi, Wang Qian, Song Yanan, Liu Taotao, Liu Yajie, Li Zhengqian #, Guo Xiangyang #. A53T α-synuclein mutation increases susceptibility to postoperative delayed neurocognitive recovery via hippocampal Ang-(1-7)/MasR axis. Biochem Pharmacol. 2024;224:116261. (Q1, IF= 5.8) (4) Li Y, Li Y, Chen L, Li Y, Liu K, Hong J, Wang Q, Kang N, Song Y, Mi X, Yuan Y, Han D, Liu T, Yang N, Guo X*, Li Z *. Reciprocal interaction between mitochondrial fission and mitophagy in postoperative delayed neurocognitive recovery in aged rats. CNS Neurosci Ther. 2023 May 19. doi: 10.1111/cns.14261 (Q1, IF= 7.035) (5) Zhengqian Li, Kaixi Liu, Xiangyang Guo. Dantrolene Available in China for Malignant Hyperthermia Treatment. Anesthesiology. 2022: 136(3):515–516. (Q1, IF= 8.986) (6) Song Y #, Liu Y #, Yuan Y, Jia X, Zhang W, Wang G, Jia Y, Wang X, Liu L, Li W, Li X, Cai N, Liu C, Li Y, Han Y, Zhou Y, Mi X, Shi C, Wang JQ, Vuylsteke A, Guo X*, Li Z *: Effects of general versus subarachnoid anaesthesia on circadian melatonin rhythm and postoperative delirium in elderly patients undergoing hip fracture surgery: A prospective cohort clinical trial. EBioMedicine 2021, 70:103490 (Q1, IF= 11.205) (7) Wang Q, Zhou J, Liu T, Yang N, Mi X, Han D, Han Y, Chen L, Liu K, Zheng H, Zhang J, Lin X, Li Y, Hong J, Li Z *, Guo X*: Predictive Value of Preoperative Profiling of Serum Metabolites for Emergence Agitation After General Anesthesia in Adult Patients. Front Mol Biosci 2021; 8: 739227 (Q2, IF=6.113) (8) He J, Liu T, Li Y, Mi X, Han D, Yang N, Chen L, Li Y, Hong J, Kuang C, Yuan Y, Cao Y, Han Y, Shi C, Li Z *, Guo X*: JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis. Int Immunopharmacol 2021, 99:107962 (Q2, IF= 5.714) (9) Zhengqian Li, Yuguang Huang, Xiangyang Guo. The brain, another potential target organ, needs early protection from SARS-CoV-2 neuroinvasion. Sci China Life Sci 2020, 63(5):771-773 (Q1, IF= 10.372) (10) Zhengqiann Li #, Taotao Liu #, Ning Yang, Dengyang Han, Xining Mi, Yue Li, Kaixi Liu, Alain Vuylsteke, Hongbin Xiang*, Xiangyang Guo*. Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain. Front Med 2020.14(5):533-541 (Q2, IF=9.927)

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