Guo Xiang Yang

1993.09-1996.07 1990.09-1993.07 1982.09-1987.07 1999.12-2000.12 1998.08-1999.01 2009.07- 、 、 、 2004.09-2009.06 、 、 1996.08-2004.08 、 1987.08-1990.08 2022 2022 2022 2011 2020 《 》 2016 - 2023 2022 1. 2030 -“ ”, 、,450 2., “ - ”,52 3.,MAMs,55 1.,1000 2. 3., AD;:,56 4. (973),“ ”;:“ ”,6 5. (973),“ ” “ ”,8 6.,α-,56 7., /Aβ,57 8., RAGE LRP1 β,70 9., NF-kB,10 10.,,32 11., BBB MCAO,20 2024 A53T α-synuclein mutation increases susceptibility to postoperative delayed neurocognitive recovery via hippocampal Ang-(1-7)/MasR axis Biochem Pharmacol 2023 Factors associated with euphoria in a large subset of cases using propofol sedation during gastrointestinal endoscopy Frontiers in Psychiatry 2022 Dantrolene Available in China for Malignant Hyperthermia Treatment Anesthesiology 2022 Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway Inflammation Research 2021 Effects of general versus subarachnoid anaesthesia on circadian melatonin rhythm and postoperative delirium in elderly patients undergoing hip fracture surgery: a prospective cohort clinical trial EBioMedicine 2021 Potential Serum Biomarkers for Postoperative Neurocognitive Disorders Based on Proteomic Analysis of Cognitive-Related Brain Regions Frontiers in Aging Neuroscience 2021 The Non-peptide Angiotensin-(1–7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats Frontiers in Aging Neuroscience 2021 Lidocaine inhibits the metastatic potential of ovarian cancer by blocking NaV1.5-mediated EMT and FAK/Paxillin signaling pathway Cancer Medicine 2020 Neurological manifestations of patients with COVID-19: potential routes of SARS-CoV-2 neuroinvasion from the periphery to the brain Frontiers of Medicine 2020 Prebiotics regulation of intestinal microbiota attenuates cognitive dysfunction induced by surgery stimulation in app/ps1 mice Aging and Disease 2020 The brain, another potential target organ, needs early protection from SARS-CoV-2 neuroinvasion Science China-Life Sciences 2019 Autophagy prevents hippocampal α-synuclein oligomerization and early cognitive dysfunction after anesthesia/surgery in aged rats Aging-US 1. 《 》,2022,:,,,;:; 2. 《 》,2012,:,,,;:. 1.,,,,,,.,2023, ZL202211597687.; 2.,,,,,.,2023,,ZL 2023 1 0357179.5; 3.,,,,,,,,.,2023, ZL202210899599.1; 4.,,,,,,,,,,.,2023, ZL202210899630.1; 5.,,,..2021, ZL 201910496014.X. 6.,,,..2021,,ZL202120588676.2 7.,,,..2019,,ZL201920215280.6 8.,,,..2023,,ZL202211700730.3 9.,,,..2023,,ZL2022 10284303.5 10.,,,,..2023,,ZL 202320218679.6, 、 、,,, 、 、. 、 、, 7, 2030-“ ” 1 、“ ” “ (973) 1 ”, 3. 81,SCI 51, 6, 5, 1; 、. 、 、 、,《 》、《 》,EBioMedicine, -, -. 48. 1., “ ”,:,,, 、 、 、 、 、,, 、,,,,.,,. 、,, β 、DNA 、; 、; 、, 、 、, Lancet EBioMedicine,. 2.,,: —, “ 、 、 ”. Anesthesiology、Anesthesia & Analgesia 《 》,,;,, 0 1; “ ”, 2,, 90% 7%., 、 、, 2,,.. 3.:, “ - - - - ”, “ - - - ”, 242., 、,, 、,. 2021 2022 “ ”, 31. 4.,:,, 、 、 、. “ ”,,,.