Zhang Zhe

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2017.8- /,,,.,, 、Y 、 、 NOA,, 3, 3. 2025.10-2027.09 (:2025YFC2708100) 2023.01-2026.12 (:82271634) 2022.12-2025.12 (:2022YFC2702600) 2022.01-2024.12 (:7222208) 2020.01-2022.12 (:81901535) 2020.01-2022.12 C (:BYSYZD2019033) 2019.01-2020.12 (:7194333) 2022. 2021,, 2020. 2018,, 2018 2017 42 (American Society of Andrology),Lalor Foundation International Travel Award [1] Zhao Q*, Fang Z*, Wang P*, Qian Z, Yang Y, Ran L, Zheng J, Tang Y, Cui X, Li YY#, Zhang Z#, Jiang H#. Polylactic Acid Micro/Nanoplastic Exposure Induces Male Reproductive Toxicity by Disrupting Spermatogenesis and Mitochondrial Dysfunction in Mice. ACS Nano. 2025 Feb 11;19(5):5589-5603. [2] Xi Y*, Gong C*, Zhang Z*, Zhu F*, Zhang Y, Tang Y, Yan L, Jiang H#, Qiao J#, Liu Q#. NAE1-mediated neddylation coordinates ubiquitination regulation of meiotic recombination during spermatogenesis. Theranostics. 2025 Feb 10;15(7):3122-3142. [3] Wang X*, Liu Q*, Zhuang Z*, Cheng J, Zhang W, Jiang Q, Guo Y, Li R, Lu X, Cui L, Weng J, Tang Y, Yue J, Gao S, Hong K, Qiao J, Jiang H#, Guo J#, Zhang Z#. Decoding the pathogenesis of spermatogenic failure in cryptorchidism through single-cell transcriptomic profiling. Cell Rep Med. 2024 Sep 17;5(9):101709. [4] Liu T*, Cao Y*, Weng J, Gao S, Jin Z, Zhang Y, Yang Y, Zhang H, Xia C, Yin X, Luo Y, He Q, Jiang H#, Wang L#, Zhang Z#. Hepatitis E virus infects human testicular tissue and Sertoli cells. Emerg Microbes Infect. 2024 Dec;13(1):2332657. [5] Li C*, Wang Y*, Mu R*, Zhao J, Yao Z, Zhai J, Jin Y, Liu R, Liu D, Hong K, Jiang H#, Zhang Z#. Urate-lowering agents do not have clinically relevant negative effects on sperm quality and reproductive hormones in men with gout: a prospective open-label cohort study. Rheumatol Int. 2024 Jul;44(7):1245-1253. [6] Zhang Z.*, Xi Y.*, Liu D.-F., Mao J.-M., Zhang H.-T., Lin H.-C., Tang W.-H., Jiang H., Hong K., and Zhao L.-M#. Sperm retrieval outcomes of contralateral testis in men with nonobstructive azoospermia and unsuccessful unilateral microdissection testicular sperm extraction. Fertility and Sterility. 2024;121(3):540-542. [7] Xi Y.*, Cao Y.L.*, Tao L.Y., Gao S.Z., Jin Z.R., Cheng J.X., Jiang H.#, and Zhang Z#. A global perspective: characteristics of infertility‐related randomized clinical trials. Andrology. 2024: 12(6):1324-1335. [8] Jin Z.*, Cao Y.*, Wen Q.*, Zhang H., Fang Z., Zhao Q., Xi Y., Luo Z., Jiang H.#, Zhang Z.#, and Hang J#. Dapagliflozin ameliorates diabetes-induced spermatogenic dysfunction by modulating the adenosine metabolism along the gut microbiota-testis axis. Scientific Reports. 2024;14(1):641. [9] Jiang Y.*, Yang J.*, Xia L.*, Wei T., Cui X., Wang D., Jin Z., Lin X., Li F., and Yang K., Lang S., Liu Y., Hang J., Zhang Z.#, Hong T.#, Wei R#. Gut microbiota–tryptophan metabolism–GLP-1 axis participates in β-cell regeneration induced by dapagliflozin. Diabetes. 2024;73(6):926-940. [10] Cao Y.*, Jin Z.*, Xi Y., Cheng J., Fang Z., Zhao Q., Weng J., Zhu J., Tang Y., Zhang Z.#, and Jiang H#. Roles of ferroptosis in type 1 diabetes induced spermatogenic dysfunction. Free Radic Biol Med. 2024;214:193-205. [11] Zhao Q.C.*, Zhang Z.*, Zhao L.M.*, Deng Z.F., Gao J.M., Zhang H.L., Lin H.C., Liu D.F., Mao J.M., Zhang H.T., Chen Y.L., Tang W.H., and Jiang H#. A retrospective cohort study of geographic differences in the semen of 1,012 sperm donors in China. Transl Androl Urol. 2023;12(2):187-196. [12] Zhao Q.*, Zhu L., Weng J., Jin Z., Cao Y., Jiang H.#, and Zhang Z#. Detection and characterization of microplastics in the human testis and semen. Sci Total Environ. 2023;877:162713. [13] Zhang Z.*, Yang Y.-Z., Zhang H.-T., Xi Y., Wang C.-T., Liu D.-F., Mao J.-M., Lin H.-C., Tang W.-H., Zhao L.-M., Zhang X.-S.#, Dai Y.-T.#, and Jiang H#. Psychological status of infertile men during the Coronavirus Disease 2019 Pandemic in China: a cross-sectional investigation. Basic and Clinical Andrology. 2023;33(1):8. [14] Zhang Z.*, Hu J.*, Xiao S., Cao Y., Chen Y., Weng J., Jiang H.#, Li W.#, Chen J.-Y.#, and Liu C#. Microhomology-mediated circular DNA formation from oligonucleosomal fragments during spermatogenesis. eLife. 2023;12:RP87115. [15] Xu W.*#, Liu C.*, Zhang Z.*, Sun C., Li Q., Li K., Jiang H.#, Li W.#, and Sun Q#. DEtail-seq is an ultra-efficient and convenient method for meiotic DNA break profiling in multiple organisms. Sci China Life Sci. 2023;66(6):1392-1407. [16] Lu X.*, Luo Y.*, Nie X.*, Zhang B., Wang X., Li R., Liu G., Zhou Q., Liu Z., Fan L., Hotaling J.M., Zhang Z.#, Bo H.#, and Guo J#. Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment. Nat Commun. 2023;14(1):8462. [17] Jin Z.*, Yang Y.*, Cao Y.*, Wen Q., Xi Y., Cheng J., Zhao Q., Weng J., Hong K., Jiang H.#, Hang J.#, and Zhang Z#. The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis. Microbiome. 2023;11(1):212. [18] Cao Y.*, Wang H.*, Jin Z.*, Hang J., Jiang H.#, Wu H.#, and Zhang Z#. Characterization of Non-Obstructive Azoospermia in Men Using Gut Microbial Profiling. J Clin Med. 2023;12(2):701. [19] Zhang Z.*, Wu H.*, Zheng L., Zhang H.-T., Yang Y.-Z., Mao J.-M., Liu D.-F., and Zhao L.-M., Liang H.#, Jiang H#. Identification and characterization of circular RNAs in the testicular tissue of patients with non-obstructive azoospermia. Asian Journal of Andrology. 2022;24(6):660-665. [20] Wang L(#), Zhang Z(#), Shu J(#), Zhang H, Yang Y, Liang Z, He Q, Huang W, Wang Y, Zhuang H, Jiang H(*), Wang L(*). Absence of hepatitis E virus RNA in semen samples of infertile male in China. Gut. 2020 Jul;69(7): 1363-1364.