Li Zhe Hai

1988 -1993,; 2004 -2007,; 2011 -2014,. 1993 -2017, 、 、 、 、; 2018 -2019,; 2020,. 1. “ rAd-col2A1-ADAM8/EGFR ”. 2. “ r AAV-BMP-2/-OA ”. 3. “ - ”. 4. “ ”. 5. “ Dkk1-siRNA ”. 《 》 6, 2. 2002 “ ”. 2012 “ ”. 2015 “ ”. [1] Li, Zhe-Hai; Hu, He; Zhang, Xiao-Yan; Liu, Guo-Dong; Ran, Bo; Zhang, Pei-Guang; Liao, Ming-Mei; Wu, Yu-Chi *. MiR-291a-3p regulates the BMSCs differentiation via targeting DKK1 in dexamethasone-induced osteoporosis. The Kaohsiung Journal of Medical Sciences. 2020, 36(1): 35-42. [2] Duan B, Liu Y, Hu H, Shi FG, Liu YL, Xue H, Yun XY, Yan MY, Han XR, Chen AF, Wang Y, Li ZH *. Notch1-ADAM8 positive feed-back loop regulates the degradation of chondrogenic extracellular matrix and osteoarthritis progression. Cell Commun Signal. 2019;17:134. [3] He Hu, Chuanlong Zhao, Peiguang Zhang, Yalong Liud, Yulian Jiang, Enquan Wu, Hao Xue, Caiyun Liu, Zhehai Li *.miR-26b modulates OA induced BMSC osteogenesis through regulating GSK3 β / β -catenin pathway. Experimental and Molecular Pathology. 2019;107:158-164. [4] He Hu, Zhehai Li,Min Lu,Xinyi Yun,Wei Li,Caiyun Liu, Ai Gu.Osteoactivin inhibits dexamethasone-induced osteoporosis through upregulating integrin β 1 and activate ERK pathway.Biomedicine & Pharmacotherapy,2018, 105: 66-72. [5] Zhehai Li, Qiande Liao, Yuchi Wu, Mingmei Liao,Yuqin Hao, Shengbin Zhang, Shipeng Song, Bing Li, Yang-de Zhang. Upregulation of a disintegrin and metalloprotease 8 influences tumor metastasis and prognosis in patients with osteosarcoma. Pathology & Oncology Research,2012,18(3):657-661. [6],,. - [J].,2011,31(11):1266-1271. [7],,.rAd-DKK1-shRNA [J].,2013,19(5):371-376. [8],,,,,, *. DKK1 、 [J].,2014,11:1290-1297. [9],,. - [J].,2002,01:37-40. [10],,. [J].,2006,09:698-701. 《 》