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Song Chun Li
Professor

Peking University Third Hospital · Orthopedics Department · Beijing

2002. 2006-2009 2009-2012 2010-2018 、 、. 2018- 、 《 》 《 Journal of Orthopaedic Translation 》 《 》 2024 2020 “ ” 2011 2010 2009 “ 863 ”,, 、,. RCT 13, 5. 100; 5, 2, 7; 1. 1. Kang Song, Xuezheng Geng, Huan Yin, Yanzhu Shi, Jiawei Wang, Jiayu Yu, Mateng Bai, Lizhen Wang, Yurui Xue, Chunli Song, Yubo Fan. Schottky engineering of GDYO@Pt to boost piezoelectric and oxidative stress modulation for accelerated cranial regeneration. Nat Commun. 2025 Sep 26;16(1):8523. doi: 10.1038/s41467-025-63550-8. 2. Liu X, Liu H, Yang G, Jiang Z, Cui S, Zhang Z, Wang H, Tao L, Sun Y, Song Z, Hong T, Yang J, Gao T, Zhang J, Li X, Zhang J, Sang Y, Yang Z, Xue K, Wu S, Zhang P, Yang J*, Song C*, Wang G*. Ageneralist medical language model for disease diagnosis assistance. Nat Med. 2025 Jan 8. DOI: 10.1038/s41591-024-03416-6 3. Zheng XQ, Wang DB, Jiang YR, Song CL*. Gut microbiota and microbial metabolites for osteoporosis. Gut Microbes. 2025;17(1):2437247. DOI: 10.1080/19490976.2024.2437247 4. Xuan-Qi Zheng, Zhi-Yuan Guan, Yun-Di Zhang, Chun-Li Song. Different role of the gut microbiota in postmenopausal and senile osteoporosis. Bone Res. 2025 Jun 13;13(1):63. doi: 10.1038/s41413-025-00432-1. 5. Wang, H, Tao, L, Cui, L, Chen, … Song C*. Randomized trial of influence of vitamin D on the prevention and improvement of symptomatic COVID-19. Sci Rep. 2024 Dec 31;14(1): 32158. DOI: 10.1038/s41598-024-66267-8 6. Wang H, Huang J, Tao L, Liu D, Song C*. Efficacy and safety of minodronate in the treatment of postmenopausal osteoporosis with low back pain: a single-center, randomized and open-label controlled trial. Trials. 2024;25(1):534. DOI: 10.1186/s13063-024-08364-7 7. Huang J, Wu T, Jiang YR, Zheng XQ, Wang H, Liu H, Wang H, Leng HJ, Fan DW, Yuan WQ, Song CL*. β-Receptor blocker enhances the anabolic effect of PTH after osteoporotic fracture. Bone Res. 2024 Mar 21;12(1):18. DOI: 10.1038/s41413-024-00321-z 8. Feng J, Huang J, Li B, Zheng X, Wang J, Wang S, Zhan S, Song C*. Association between weather and hip fracture in adults: a nationwide study in China 198 cities. Arch Osteoporos. 2023;18(1):70. DOI: 10.1007/s11657-023-01248-4 9. Guan Z, Xuanqi Z, Zhu J, Yuan W, Jia J, Zhang C, Sun T, Leng H, Jiang C, Xu Y, Song C*. Estrogen deficiency induces bone loss through the gut microbiota. Pharmacol Res. 2023 Oct;196:106930. DOI: 10.1016/j.phrs.2023.106930 10. Zheng XQ, Lin JL, Huang J, Wu T, Song CL*. Targeting aging with the healthy skeletal system: The endocrine role of bone. Rev Endocr Metab Disord. 2023 Aug;24(4):695-711. DOI: 10.1007/s11154-023-09812-6 11. 2023 163 281-289 12., 2023 1603 281-289 13. Zheng XQ, Xu L, Huang J, Zhang CG, Yuan WQ, Sun CG, Zhang ZS, Wei C, Wang JX, Cummings SR, Xia WB, Wang SF, Zhan SY, Song CL*. Incidence and cost of vertebral fracture in urban China: a 5-year population-based cohort study. Int J Surg. 2023 Jul 1;109(7):1910-1918. DOI:10.1097/JS9.0000000000000411 (Q1, IF:12.5) 14. Zheng XQ, Huang J, Lin JL, Song CL*. Pathophysiological mechanism of acute bone loss after fracture. J Adv Res. 2023 Jul;49:63-80. DOI: 10.1016/j.jare.2022.08.019 15. Guan Z, Yuan W, Jia J, Zhang C, Zhu J, Huang J, Zhang W, Fan D, Leng H, Li Z, Xu Y, Song C*. Bone mass loss in chronic heart failure is associated with sympathetic nerve activation. Bone. 2023 Jan; 166:116596. DOI: 10.1016/j.bone.2022.116596 16. Yuan W, Ren X, Zhu J, Huang J, Zhang W, Zhang C, Guan Z, Wang H, Leng H, Song C*. Single-intraosseous simvastatin injection suppresses cancers via activating CD8+ T cells. Biomed Pharmacother. 2022; 155:113665. DOI: 10.1016/j.biopha.2022.113665 17. Sun T, Huang J, Zhang W, Zheng X, Wang H, Liu J, Leng H, Yuan W, Song C*. Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections. Bioact Mater. 2022 Aug 13;21:44-56. DOI: 10.1016/ j. bioactmat.2022.07.028 18. Zhang C, Zhu J, Jia J, Guan Z, Sun T, Zhang W, Yuan W, Wang H, Song C*. Long-term pretreatment with alendronate inhibits calvarial defect healing in an osteoporotic rat model. J Bone Miner Metab. 2021 Nov;39(6):925-933. DOI: 10.1007/s00774-021-01235-0 19. Zhang C, Zhu J, Jia J, Guan Z, SunT, Zhang W, Yuan W, Wang H, Leng H, Song C*. Effect of Single Versus Multiple Fractures on Systemic Bone Loss in Mice. J Bone Miner Res. 2021 Mar;36(3):567-578. DOI: 10.1002/jbmr.4211 20. Pan Z, Chu H, Zhang Y, Hong X, Liang L, Zhao W, Chen Y, Song C*. Perspectives of research ethics committee members on human challenge studies in the development of vaccines against COVID-19: a mixed methods study. Ann Palliat Med. 2021 Jun;10(6):6259-6269. DOI: 10.21037/apm-20-2622 21. Dang L, Zhu J, Song C*. The effect of topical administration of simvastatin on entochondrostosis and intramembranous ossification: An animal experiment. J Orthop Translat. 2021 Jan 27; 28:1-9. DOI: 10.1016/j.jot.2020.11.009 22. Zhang C, Zhu J, Jia J, Guan Z, Sun T, Zhang W, Yuan W, Wang H, Leng H, Song C*. Effect of Single Versus Multiple Fractures on Systemic Bone Loss in Mice. J Bone Miner Res. 2021 Mar;36(3):567-578. DOI: 10.1002/jbmr.4211 23. Zhang C, Zhu J, Jia J, Guan Z, Sun T, Zhang W, Yuan W, Wang H, Leng H, Song C*. Once-weekly parathyroid hormone combined with ongoing long-term alendronate treatment promotes osteoporotic fracture healing in ovariectomized rats. J Orthop Res. 2021 Oct;39(10):2103-2115. DOI: 10.1002/jor.24953 24. Zhang C, Song C*. Combination Therapy of PTH and Antiresorptive Drugs on Osteoporosis: A Review of Treatment Alternatives. Front Pharmacol. 2021 Jan 27; 11: 607017. DOI: 10.3389/ fphar.2020.607017 25. Liu Q, Bi G, Chen G, Guo X, Tu S, Tong X, Xu M, Liu M, Wang B, Jiang H, Wang J, Li H, Wang K, Liu D, Song C*. Time-Dependent Distribution of Hydroxychloroquine in Cynomolgus Macaques Using Population Pharmacokinetic Modeling Method. Front Pharmacol. 2021 Jan 14; 11:602880. DOI: 10.3389/fphar.2020.602880 26., 2020 13 61-67 27. Zhu J, Zhang C, Jia J, Yuan W, Zhang M, Leng H, Song C*. Effect of weekly teriparatide injections on osteoporotic fracture healing: protocol for a double-blind, randomised controlled trial. BMJ Open. 2021 Apr 1;11(4):e043137. DOI: 10.1136/bmjopen-2020-043137 28. Zhu J, Zhang C, Jia J, Wang H, Leng H, Xu Y, Wu C, Zhang Q, Song C*. Osteogenic effects in a rat osteoporosis model and femur defect model by simvastatin microcrystals. Ann N Y Acad Sci. 2021 Mar;1487(1):31-42. DOI: 10.1111/nyas.14513 29. Zhang W, Sun C, Zhu J, Zhang W, Leng H, Song C*. 3D printed porous titanium cages filled with simvastatin hydrogel promotes bone ingrowth and spinal fusion in rhesus macaques. Biomater Sci. 2020 Aug 7;8(15):4147-4156. DOI: 10.1039/d0bm00361a 30. Yuan W, Song C*. The Emerging Role of Rab5 in Membrane Receptor Trafficking and Signaling Pathways. Biochem Res Int. 2020 Feb 11; 2020:4186308. DOI: 10.1155/2020/ 4186308 31. Zhang C, Feng J, Wang S, Gao P, Xu L, Zhu J, Jia J, Liu L, Liu G, Wang J, Zhan S, Song C*. Incidence of and trends in hip fracture among adults in urban China: A nationwide retrospective cohort study. PLoS Med.2020 Aug 6;17(8):e1003180. DOI: 10.1371/journal.pmed.1003180 32. Yuan W, Hai B, Ren X, Zhu J, Zhang C, Guan Z, Jia J, Wang H, Cao B, Song C*. Single-dose local intraosseous injection of simvastatin suppresses breast cancer with tumor vascular normalization. Transl Oncol. 2020 Dec;13(12):100867. DOI: 10.1016/j.tranon.2020.100867 33. Guan Z, Guan X, Gu K, Lin X, Lin J, Zhou W, Xu M, Wan F, Zhang Z, Song C*. Short-term outcomes of on- vs off-pump coronary artery bypass grafting in patients with left ventricular dysfunction: a systematic review and meta-analysis. J Cardiothorac Surg. 2020 May 11;15(1):84. DOI: 10.1186/s13019-020-01115-0 34. Zhu J, Liu C, Jia J, Zhang C, Yuan W, Leng H, Xu Y, Song C*. Short-term caloric restriction induced bone loss in both axial and appendicular bones by increasing adiponectin. Ann N Y Acad Sci. 2020 Aug;1474(1):47-60. DOI: 10.1111/nyas.14380 35. Guan X, Guan Z, Song C*. Expression profile analysis identifies key genes as prognostic markers for metastasis of osteosarcoma. Cancer Cell Int. 2020 Mar 30; 20: 104. DOI: 10.1186/s12935-020-01179-x 36. Liu C, Zhu J, Hai B, Zhang W, Wang H, Leng H, Xu Y, Song C*. Single Intraosseous Injection of Simvastatin Promotes Endothelial Progenitor Cell Mobilization, Neovascularization, and Wound Healing in Diabetic Rats. Plast Reconstr Surg. 2020 Feb;145(2):433-443. DOI: 10.1097/PRS.0000000000006502 37. Yuan W, Hai B, Ren X, Zhu J, Zhang C, Guan Z, Jia J, Wang H, Cao B, Song C*. Single-dose local intraosseous injection of simvastatin suppresses breast cancer with tumor vascular normalization. Transl Oncol. 2020 Dec;13(12):100867. doi: 10.1016/j.tranon.2020.100867. Epub 2020 Sep 18. DOI: 10.1016/j.tranon.2020.100867 38. Guan Z, Jia J, Zhang C, Sun T, Zhang W, Yuan W, Leng H, Song C*. Gut microbiome dysbiosis alleviates the progression of osteoarthritis in mice. Clin Sci (Lond). 2020 Dec 11;134(23):3159-3174. DOI: 10.1042/CS20201224 (Q1, IF:6.7) 39. Zhang C, Zhu J, Jia J, Guan Z, Sun T, Zhang W, Yuan W, Wang H, Leng H, Song C*. Effect of Single Versus Multiple Fractures on Systemic Bone Loss in Mice. J Bone Miner Res. 2021 Mar;36(3):567-578. DOI: 10.1002/jbmr.4211 40. Dang L, Zhu J, Liu Z, Liu X, Jiang L, Wei F, Song C*. A new approach to the treatment of spinal instability: Fusion or structural reinforcement without surgery? Med Hypotheses. 2020 Nov;144:109900. DOI: 10.1016/j.mehy.2020.109900 41., 2019 12 5511-516 42., 2018 246 806-813 43. Guo Q, Liu C, Hai B, Ma T, Zhang W, Tan J, Fu X, Wang H, Xu Y, Song C*. Chitosan conduits filled with simvastatin/Pluronic F-127 hydrogel promote peripheral nerve regeneration in rats. J Biomed Mater Res B Appl Biomater. 2018 Feb;106(2):787-799. DOI: 10.1002/jbm.b.33890 44. Zhang W, Zhu J, Ma T, Liu C, Hai B, Du G, Wang H, Li N, Leng H, Xu Y, Song C*. Comparison of the effects of once-weekly and once-daily rhPTH (1-34) injections on promoting fracture healing in rodents. J Orthop Res. 2018 Apr;36(4):1145-1152. DOI: 10.1002/jor.23750 en 1. 《 》,; 2. 《 》,; 3. 《 》,; 4. 《 》,; 5. 《 》,; 6. 《 》,; 7. 《 》,,; 8. 《 》,.

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