Hong Tian Pei

1991,,. Steno.1993 、 、.2001 、 、.2009.2003 、.2014 2018.2024. 《 》,, 《2 》、《 2 》、《 2 》、《 》、《 - 2 2 (2023 )》 10, 70. 、 、. 3 0, 9 ( 7 、 1 、 1 )、 1 、 1 、 973 2 、 863 1.,: [1],,2024/08-2028/07,200 [2]:2 、,2018.8~2020.12,1222 [3]: α β,2019.1~2023.12,352 、, 、 、. ADA ( Diabetes Care/Diabetes ), Diabetology & Metabolic Syndrome, 、 、 7, Journal of Diabetes Investigation 、 Chronic Disease & Translational Medicine 、 、 、 、; BMJ 、 Diabetes Care 、 Diabetes 、 Diabetologia 、 Metabolism 、 Diabetes Obesity and Metabolism 、 Journal of Clinical Endocrinology & Metabolism 、 Nature Communications 、 Advanced Science 、 Cell Death and Differentiation 4 0 SCI. 2016,; 2015,; 1996., 2018, “ - ”; 2018, “ ”; 2018, “ ”; 2017, -. 400. JAMA、Diabetes、Diabetologia、Metabolism、Diabetes Obesity and Metabolism SCI 100.: [1] Wang D, Wei T, Cui X, Xia L, Jiang Y, Yin D, Liao X, Li F, Li J, Wu Q, Lin X, Lang S, Le Y, Yang J, Yang J, Wei R, Hong T. Fam3a-mediated prohormone convertase switch in α-cells regulates pancreatic GLP-1 production in an Nr4a2-Foxa2-dependent manner. Metabolism. 2024 Oct 1:156042. doi: 10.1016/j.metabol.2024.156042. IF = 10.8 [2] Lin XF, Cui XN, Yang J, Jiang YF, Wei TJ, Xia L, Liao XY, Li F, Wang DD, Li J, Wu Q, Yin DS, Le YY, Yang K, Wei R, Hong T. SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization. Acta Pharmacol Sin. 2024 Sep 18. doi: 10.1038/s41401-024-01389-3. IF = 8.2 [3] Li F, Si W, Xia L, Yin D, Wei T, Tao M, Cui X, Yang J, Hong T *, Wei R*. Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma. Mol Cancer. 2024; 23(1):90. IF = 37.3 [4] Jiang Y, Yang J, Xia L, Wei T, Cui X, Wang D, Jin Z, Lin X, Li F, Yang K, Lang S, Liu Y, Hang J, Zhang Z*, Hong T *, Wei R*. Gut microbiota-tryptophan metabolism-GLP-1 axis participates in β-cell regeneration induced by dapagliflozin. Diabetes. 2024; 73(6):926-940. IF = 7.7 [5] Wei T, Cui X, Jiang Y, Wang K, Wang D, Li F, Lin X, Gu L, Yang K, Yang J, Hong T *, Wei R*. Glucagon Acting at the GLP-1 Receptor Contributes to β-Cell Regeneration Induced by Glucagon Receptor Antagonism in Diabetic Mice. Diabetes. 2023; 72(5):599-610. IF = 9.337 [6] Cui X, Feng J, Wei T, Zhang L, Lang S, Yang K, Yang J, Liu J, Sterr M, Lickert H, Wei R, Hong T. Pancreatic alpha cell glucagon-liver FGF21 axis regulates beta cell regeneration in a mouse model of type 2 diabetes. Diabetologia. 2023; 66(3):535-550. IF = 10.460 [7] Cui X, Feng J, Wei T, Gu L, Wang D, Lang S, Yang K, Yang J, Yan H, Wei R, Hong T. Pro-α-cell-derived β-cells contribute to β-cell neogenesis induced by antagonistic glucagon receptor antibody in type 2 diabetic mice. iScience. 2022; 25(7):104567. IF = 6.107 [8] Hong T, Su Q, Li X, Shan Z, Chen L, Peng Y, Chen L, Yan L, Bao Y, Lyu Z, Shi L, Wang W, Guo L, Ning G, Mu Y, Zhu D. Glucose-lowering pharmacotherapies in Chinese adults with type 2 diabetes and cardiovascular disease or chronic kidney disease. An expert consensus reported by the Chinese Diabetes Society and the Chinese Society of Endocrinology. Diabetes Metab Res Rev. 2021; 37(4):e3416. IF = 8.128 [9] Wei R, Cui X, Feng J, Gu L, Lang S, Wei T, Yang J, Liu J, Le Y, Wang H, Yang K, Hong T. Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice. Metabolism. 2020; 111:154324. IF = 13.934 [10] Yang J, Xiao W, Guo L, Li Q, Zhong L, Yang J, Yang J, Gao Y, Tian Q, Hong T. Efficacy and safety of generic exenatide injection in Chinese patients with type 2 diabetes: a multicenter, randomized, controlled, non-inferiority trial. Acta Diabetol. 2020; 57(8):991-1000. IF = 4.280 [11] Liu J, Yang K, Yang J, Xiao W, Le Y, Yu F, Gu L, Lang S, Tian Q, Jin T, Wei R, Hong T. Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output. EBioMedicine. 2019; 41:73-84. IF = 11.205 [12] Si W, Liu X, Wei R, Zhang Y, Zhao Y, Cui L, Hong T. MTA2-mediated inhibition of PTEN leads to pancreatic ductal adenocarcinoma carcinogenicity. Cell Death Dis 2019; 10(3):206. IF = 8.469 [13] Wei R, Gu L, Yang J, Yang K, Liu J, Le Y, Lang S, Wang H, Thai D, Yan H, Hong T. Antagonistic glucagon receptor antibody promotes a-cell proliferation and increases b-cell mass in diabetic mice. iScience. 2019; 16:326-339. IF = 6.107 [14] Wang P, Lv C, Zhang T, Liu J, Yang J, Guan F, Hong T. FOXQ1 regulates senescence-associated inflammation via activation SIRT1 expression. Cell Death Dis 2017; 8: e2946. IF = 6.304 [15] Wang H, Gao H, Chi H, Zeng L, Xiao W, Wang Y, Li R, Liu P, Wang C, Tian Q, Zhou Z, Yang J, Liu Y, Wei R, Mol BWJ, Hong T *, Qiao J*. Effect of Levothyroxine on Miscarriage Among Women With Normal Thyroid Function and Thyroid Autoimmunity Undergoing In Vitro Fertilization and Embryo Transfer: A Randomized Clinical Trial. JAMA 2017; 318(22):2190-2198. IF = 47.661 《 》、《 》、《: 》、《 》、《 》 7., 《 Williams ( 14 ) 》、《 》、《 》、《 》 10., 《 》、《 》、《 》、《 》、《 》、《 》、《 》 3 0.