Autoimmune liver disease

Autoimmune liver disease is a type of autoimmune disease in which the liver is the organ with relatively specific immunopathological injury. It mainly includes: autoimmune hepatitis (AIH), primary biliary cirrhosis (PBS), and primary sclerosing cholangitis (PSC), as well as overlap syndromes between any two of these three diseases, often accompanied by extrahepatic immune diseases. Its diagnosis is mainly based on specific biochemical abnormalities, autoantibodies, and characteristic histological features. With improved awareness and diagnostic capabilities, the reported prevalence of autoimmune liver disease has been increasing year by year both domestically and internationally, thus attracting increasing attention and concern.