Turcot syndrome

Familial colonic adenomatosis with multiple tumor syndrome was proposed by Turcot in 1959, hence also called Turcot syndrome. This disease is characterized by familial colonic polyposis accompanied by tumors elsewhere in the body, usually combined with central nervous system tumors, such as medulloblastoma and glioblastoma, also known as glioma-polyposis syndrome. It is clinically rare, an autosomal recessive hereditary disease, affecting both males and females, with an onset age of 2 to 84 years, averaging 17 years, and is more common in young people.