Takayasu arteritis

Takayasu's arteritis, also known as primary arteritis syndrome, aortic arch syndrome, or pulseless disease, is more common in young women. Takayasu's arteritis refers to a chronic non-specific inflammation mainly involving the walls of large arteries, which can lead to segmental arterial stenosis and even occlusion, and may be complicated by secondary thrombosis. The pulmonary artery and coronary arteries are also often involved. A few cases are complicated by aneurysmal dilation. Due to the unknown etiology and complex clinical manifestations of this disease, it has many names, such as aortic arch syndrome, chronic subclavian artery and carotid artery obstruction syndrome, idiopathic arteritis, arteritis in young women, arteritis, etc. In China, it is called Takayasu's arteritis. This disease mainly involves the aorta and its major branches, thus potentially affecting the blood supply to the head, upper limbs, lower limbs, and internal organs. In recent years, it has been considered an autoimmune disease related to the deposition of immune complexes, and most cases may be associated with certain infections. Currently, most believe it is an autoimmune disease possibly related to infections such as streptococcus, tuberculosis bacillus, and viruses. Some patients have been found to have anti-aortic antibodies, but their etiological role is uncertain.