Congestive splenomegaly

Congestive splenomegaly is caused by portal hypertension resulting from liver cirrhosis, or inflammation or thrombosis of the portal or splenic vein. It is often accompanied by manifestations of liver cirrhosis and portal hypertension, such as varices of the lower esophagus or gastric fundus, ascites, and dyspepsia. It is also accompanied by hypersplenism, manifested as the "three decreases" phenomenon in which red blood cells, white blood cells, and platelets are all reduced. At the same time, bone marrow hematopoietic function is vigorous.