Mesenteric panniculitis

Mesenteric panniculitis is a rare mesenteric disorder, clinically manifested mainly by abdominal pain and an abdominal mass. In 1960, Dgder elaborated on the pathological process of this disease, pointing out that it is caused by non-specific inflammation leading to extensive thickening of the mesentery, followed by fibrosis. Therefore, it is also known as mesenteric lipohypertrophy, mesenteric lipogranuloma, primary mesenteric liposclerosis, isolated mesenteric lipodystrophy, retractile mesenteritis, Weber-Christian disease, and idiopathic sclerosing mesenteritis. Most patients with this disease have a history of trauma or abdominal surgery, so the occurrence of this disease may be related to factors such as abdominal trauma, abdominal surgery, infection, and allergic reactions. There are many defects that can lead to this disease. The lesions mainly affect the mesentery of the small intestine, most commonly at the root of the mesentery, and may also spread to the intestinal wall, but are usually relatively localized. Patients generally present with loss of appetite, weakness, and weight loss, with the main manifestation being abdominal pain, most commonly in the right lower abdomen; left-sided abdominal pain and upper abdominal pain can also occur but are less common. This disease has a tendency toward self-limitation, and generally, with supportive treatment, the patient's symptoms can be alleviated.