Megaloblastic anemia

Megaloblastic anemia is a type of anemia caused by impaired deoxyribonucleic acid (DNA) synthesis, mainly due to deficiency of vitamin B12 or folic acid in the body, and can also be caused by acquired DNA synthesis disorders due to genetic factors or drugs. The characteristic of this disease is macrocytic anemia, with the appearance of megaloblastic series in the bone marrow, and the giant morphological changes of cells are also seen in the granulocytic and megakaryocytic series, and even in certain proliferative somatic cells. This disease is more common in populations in Shaanxi, Shanxi, Henan, and other areas who consume fewer fresh vegetables and meats.