Coagulation disorders

Coagulation disorders refer to hemorrhagic diseases caused by deficiency or functional abnormalities of coagulation factors. They can be divided into two major categories: hereditary and acquired. Hereditary coagulation disorders are generally due to a deficiency of a single coagulation factor, often presenting with bleeding symptoms in infancy and usually having a family history. Acquired coagulation disorders are more common; patients often have deficiencies of multiple coagulation factors, mostly occurring in adulthood, and clinically, in addition to bleeding, they also present with symptoms and signs of the underlying disease. Such diseases include hemophilia, vitamin K deficiency, von Willebrand disease, disseminated intravascular coagulation, etc.